ea0041ep787 | Obesity | ECE2016
Bekaert Marlies
, Margriet Ouwens D
, Horbelt Tina
, Van de Velde Frederique
, Van Nieuwenhove Yves
, Calders Patrick
, Praet Marleen
, Geerts Anja
, Verhelst Xavier
, Kaufman Jean-Marc
, Lapauw Bruno
Aims: Emerging data indicate that an impaired release of adipose tissue-derived adipokines could play a pivotal role in the development of non-alcoholic fatty liver disease (NAFLD). We aimed to evaluate whether circulating levels or visceral adipose tissue (VAT) expression of recently described adipokines associate with the histopathological disease severity and thus may contribute to the progression of pure fatty liver into an inflammatory and insulin resistant NASH status.</...